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S100a3 S100 calcium binding protein A3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 114216, updated on 17-Aug-2024

Summary

Official Symbol
S100a3provided by RGD
Official Full Name
S100 calcium binding protein A3provided by RGD
Primary source
RGD:620260
See related
EnsemblRapid:ENSRNOG00000012008 AllianceGenome:RGD:620260
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Predicted to be located in Golgi apparatus; cytosol; and plasma membrane. Orthologous to human S100A3 (S100 calcium binding protein A3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 11.9), Spleen (RPKM 7.7) and 6 other tissues See more
Orthologs
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Genomic context

See S100a3 in Genome Data Viewer
Location:
2q34
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (178331856..178387280)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (176034283..176089702)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (189955619..189996029)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene S100 calcium binding protein A16 Neighboring gene U6 spliceosomal RNA Neighboring gene MIER family member 3, pseudogene 1 Neighboring gene S100 calcium binding protein A2 Neighboring gene S100 calcium-binding protein A4 Neighboring gene S100 calcium binding protein A5

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables calcium-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transition metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053681.1NP_446133.1  protein S100-A3

    See identical proteins and their annotated locations for NP_446133.1

    Status: PROVISIONAL

    Source sequence(s)
    AF140231
    UniProtKB/Swiss-Prot
    P62819
    UniProtKB/TrEMBL
    A0A8L2Q7T6, A6J6P6
    Conserved Domains (1) summary
    cd00213
    Location:490
    S-100; S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 proteins are ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    178331856..178387280
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039101554.2XP_038957482.1  protein S100-A3 isoform X2

    UniProtKB/TrEMBL
    A0A0G2K8A2, A0A8L2Q7T6, A6J6P3
    Conserved Domains (1) summary
    cd00213
    Location:1298
    S-100; S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 proteins are ...
  2. XM_008761122.4XP_008759344.1  protein S100-A3 isoform X2

    See identical proteins and their annotated locations for XP_008759344.1

    UniProtKB/TrEMBL
    A0A0G2K8A2, A0A8L2Q7T6, A6J6P3
    Conserved Domains (1) summary
    cd00213
    Location:1298
    S-100; S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 proteins are ...
  3. XM_006232559.5XP_006232621.1  protein S100-A3 isoform X3

    See identical proteins and their annotated locations for XP_006232621.1

    UniProtKB/Swiss-Prot
    P62819
    UniProtKB/TrEMBL
    A0A8L2Q7T6, A6J6P6
    Conserved Domains (1) summary
    cd00213
    Location:490
    S-100; S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 proteins are ...
  4. XM_017590578.3XP_017446067.1  protein S100-A3 isoform X3

    UniProtKB/Swiss-Prot
    P62819
    UniProtKB/TrEMBL
    A0A8L2Q7T6, A6J6P6
    Conserved Domains (1) summary
    cd00213
    Location:490
    S-100; S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 proteins are ...
  5. XM_017590577.3XP_017446066.1  protein S100-A3 isoform X3

    UniProtKB/Swiss-Prot
    P62819
    UniProtKB/TrEMBL
    A0A8L2Q7T6, A6J6P6
    Conserved Domains (1) summary
    cd00213
    Location:490
    S-100; S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 proteins are ...
  6. XM_006232560.5XP_006232622.1  protein S100-A3 isoform X3

    See identical proteins and their annotated locations for XP_006232622.1

    UniProtKB/Swiss-Prot
    P62819
    UniProtKB/TrEMBL
    A0A8L2Q7T6, A6J6P6
    Conserved Domains (1) summary
    cd00213
    Location:490
    S-100; S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 proteins are ...
  7. XM_006232558.5XP_006232620.1  protein S100-A3 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A319, A0A8L2Q7T6
    Related
    ENSRNOP00000085336.1, ENSRNOT00000108343.2
    Conserved Domains (1) summary
    cd00213
    Location:16102
    S-100; S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 ...
  8. XM_017590580.3XP_017446069.1  protein S100-A3 isoform X3

    UniProtKB/Swiss-Prot
    P62819
    UniProtKB/TrEMBL
    A0A8L2Q7T6, A6J6P6
    Conserved Domains (1) summary
    cd00213
    Location:490
    S-100; S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 proteins are ...
  9. XM_006232563.5XP_006232625.1  protein S100-A3 isoform X3

    See identical proteins and their annotated locations for XP_006232625.1

    UniProtKB/Swiss-Prot
    P62819
    UniProtKB/TrEMBL
    A0A8L2Q7T6, A6J6P6
    Conserved Domains (1) summary
    cd00213
    Location:490
    S-100; S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 proteins are ...