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GRK3 G protein-coupled receptor kinase 3 [ Rhinatrema bivittatum (two-lined caecilian) ]

Gene ID: 115100981, updated on 17-Mar-2024

Summary

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Gene symbol
GRK3
Gene description
G protein-coupled receptor kinase 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinatrema bivittatum
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Gymnophiona; Rhinatrematidae; Rhinatrema
Orthologs
human mouse all
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Genomic context

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See GRK3 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
23
Annotation release Status Assembly Chr Location
100 current aRhiBiv1.1 (GCF_901001135.1) 11 NC_042625.1 (18429575..18981245, complement)

Chromosome 11 - NC_042625.1Genomic Context describing neighboring genes Neighboring gene ETS domain-containing transcription factor ERF-like Neighboring gene myosin XVIIIB Neighboring gene uncharacterized LOC115100983 Neighboring gene tigger transposable element-derived protein 1-like Neighboring gene beta-crystallin B2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_042625.1 Chromosome 11 Reference aRhiBiv1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multi-tissue transcriptomes of caecilian amphibians highlight incomplete knowledge of vertebrate gene families. Torres-Sánchez M, et al. DNA Res, 2019 Feb 1. PMID 30351380, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G protein-coupled receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G protein-coupled receptor kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-adrenergic receptor kinase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rhinatrema bivittatum Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aRhiBiv1.1 Primary Assembly

Genomic

  1. NC_042625.1 Reference aRhiBiv1.1 Primary Assembly

    Range
    18429575..18981245 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029620117.1 → XP_029475977.1  beta-adrenergic receptor kinase 2 isoform X3

  2. XM_029620115.1 → XP_029475975.1  beta-adrenergic receptor kinase 2 isoform X1

  3. XM_029620116.1 → XP_029475976.1  beta-adrenergic receptor kinase 2 isoform X2

    Conserved Domains (3) summary
    cd08747
    Location:30 → 186
    RGS_GRK2_GRK3; Regulator of G protein signaling domain (RGS) found in G protein-coupled receptor kinase 2 (GRK2) and G protein-coupled receptor kinase 3 (GRK3)
    cd01240
    Location:553 → 670
    PH_GRK2_subgroup; G Protein-Coupled Receptor Kinase 2 subgroup pleckstrin homology (PH) domain
    cl21453
    Location:185 → 530
    PKc_like; Protein Kinases, catalytic domain

  4. XM_029620118.1 → XP_029475978.1  beta-adrenergic receptor kinase 2 isoform X4

    Conserved Domains (3) summary
    cd01240
    Location:481 → 598
    PH_GRK2_subgroup; G Protein-Coupled Receptor Kinase 2 subgroup pleckstrin homology (PH) domain
    cl02565
    Location:1 → 114
    RGS; Regulator of G protein signaling (RGS) domain superfamily
    cl21453
    Location:113 → 458
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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