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ncf4 neutrophil cytosolic factor 4 [ Sparus aurata (gilthead seabream) ]

Gene ID: 115581486, updated on 17-Mar-2024

Summary

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Gene symbol
ncf4
Gene description
neutrophil cytosolic factor 4
See related
Ensembl:ENSSAUG00010014551
Gene type
protein coding
RefSeq status
MODEL
Organism
Sparus aurata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Spariformes; Sparidae; Sparus
Orthologs
human zebrafish all
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Genomic context

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See ncf4 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
10
Annotation release Status Assembly Chr Location
100 current fSpaAur1.1 (GCF_900880675.1) 1 NC_044187.1 (8330162..8365912, complement)

Chromosome 1 - NC_044187.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene ell-associated factor Eaf-like Neighboring gene parvalbumin 7 Neighboring gene uncharacterized LOC115581502 Neighboring gene BAR/IMD domain containing adaptor protein 2 like 2b Neighboring gene dynein heavy chain domain-containing protein 1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_044187.1 Chromosome 1 Reference fSpaAur1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pattern of expression of immune-relevant genes in the gonad of a teleost, the gilthead seabream (Sparus aurata L.). Chaves-Pozo E, et al. Mol Immunol, 2008 May. PMID 18325594
  2. Vaccination of larvae of the bony fish gilthead seabream reveals a lack of correlation between lymphocyte development and adaptive immunocompetence. Mulero I, et al. Mol Immunol, 2008 May. PMID 18325592

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables superoxide-generating NADPH oxidase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phagocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in respiratory burst IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in superoxide anion generation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NADPH oxidase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neutrophil cytosol factor 4
Names
p40phox protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sparus aurata Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fSpaAur1.1 Primary Assembly

Genomic

  1. NC_044187.1 Reference fSpaAur1.1 Primary Assembly

    Range
    8330162..8365912 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030416617.1 → XP_030272477.1  neutrophil cytosol factor 4

    UniProtKB/TrEMBL
    A0A671W7H9, A0A671W7I3
    Related
    ENSSAUP00010034619.1, ENSSAUT00010036469.1
    Conserved Domains (3) summary
    cd06882
    Location:19 → 143
    PX_p40phox; The phosphoinositide binding Phox Homology domain of the p40phox subunit of NADPH oxidase
    cl02720
    Location:244 → 337
    PB1; The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 ...
    cl17036
    Location:173 → 226
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
Heading Accession and Version

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