Pcdha12 protocadherin alpha 12 [Rattus norvegicus (Norway rat)] - Gene

Summary

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Official Symbol: Pcdha12provided by RGD
Official Full Name: protocadherin alpha 12provided by RGD
Primary source: RGD:620750
See related: AllianceGenome:RGD:620750
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: rCNRv12
Summary: Predicted to enable calcium ion binding activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in membrane. Orthologous to human PCDHA12 (protocadherin alpha 12). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information: not in current annotation release
Expression: Biased expression in Brain (RPKM 148.0), Lung (RPKM 101.4) and 6 other tissues See more
Orthologs: human mouse all
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Genomic context

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See Pcdha12 in Genome Data Viewer

Location:: 18p11

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

BF389688 (e-PCR)
- UniSTS:245509

PMC312645P1 (e-PCR)
- UniSTS:272906

RH91795 (e-PCR)
- UniSTS:85819

IB766 (e-PCR)
- UniSTS:42573

WI-19540 (e-PCR)
- UniSTS:63886

NoName (e-PCR)
- UniSTS:547524

Pcdha (e-PCR), detects polymorphism
- UniSTS:547524

RH65516 (e-PCR)
- UniSTS:66009

PMC311048P1 (e-PCR)
- UniSTS:272867

Gene Ontology Provided by RGD

Component	Evidence Code	Pubs
located_in membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: protocadherin alpha 12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_053940.1 → NP_446392.1 protocadherin alpha 12 precursor

See identical proteins and their annotated locations for NP_446392.1

Status: PROVISIONAL

Source sequence(s)

AB113395

UniProtKB/TrEMBL

Q593Y1, Q767I0

Conserved Domains (3) summary

cd11304
Location:246 → 345

Cadherin_repeat; Cadherin tandem repeat domain

pfam08266
Location:30 → 111

Cadherin_2; Cadherin-like

pfam15974
Location:799 → 942

Cadherin_tail; Cadherin C-terminal cytoplasmic tail, catenin-binding region