Il22b interleukin 22B [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Il22bprovided by MGI
Official Full Name: interleukin 22Bprovided by MGI
Primary source: MGI:MGI:2151139
See related: Ensembl:ENSMUSG00000090461 AllianceGenome:MGI:2151139
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: If2b2; IL-22b; Iltifb; IL-TIFb
Summary: Predicted to enable cytokine activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular space. Is expressed in retina. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL22 (interleukin 22). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Restricted expression toward cerebellum adult (RPKM 5.6) See more
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Genomic context

Location:: 10 D2; 10 66.7 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	10	NC_000076.7 (118125534..118130943, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	10	NC_000076.6 (118289629..118295038, complement)

Chromosome 10 - NC_000076.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

General gene information

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Markers

NoName (e-PCR)
- UniSTS:487626

Iltif (e-PCR), detects polymorphism
- UniSTS:233956

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables cytokine activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: interleukin-22b

Names: IL-10-related T-cell-derived-inducible factor beta; IL-TIF beta; interferon 2b2; interleukin 10-related T cell-derived inducible factor beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.