Arl5a ARF like GTPase 5A [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Arl5aprovided by RGD
Official Full Name: ARF like GTPase 5Aprovided by RGD
Primary source: RGD:621327
See related: EnsemblRapid:ENSRNOG00000006839 AllianceGenome:RGD:621327
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Arl5
Summary: Predicted to enable GTP binding activity. Predicted to be involved in intracellular protein transport; protein localization to Golgi membrane; and vesicle-mediated transport. Predicted to be active in trans-Golgi network. Orthologous to human ARL5A (ADP ribosylation factor like GTPase 5A). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Lung (RPKM 255.9), Heart (RPKM 254.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 3q12

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (57287599..57312488, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (36878461..36903362, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (37922544..37947434, complement)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables GTP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTP binding	TAS Traceable Author Statement more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein localization to Golgi membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein localization to Golgi membrane	ISO Inferred from Sequence Orthology more info
involved_in vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in trans-Golgi network	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ADP-ribosylation factor-like protein 5A

Names: ADP-ribosylation factor like GTPase 5A; ADP-ribosylation factor-like 5; ADP-ribosylation factor-like 5A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_053979.2 → NP_446431.1 ADP-ribosylation factor-like protein 5A

See identical proteins and their annotated locations for NP_446431.1

Status: PROVISIONAL

Source sequence(s)

BC097294

UniProtKB/Swiss-Prot

P51646, Q4V8N2

UniProtKB/TrEMBL

A6JF24

Related

ENSRNOP00000009181.1, ENSRNOT00000009181.4

Conserved Domains (1) summary

cd04153
Location:3 → 175

Arl5_Arl8; Arf-like 5 (Arl5) and 8 (Arl8) GTPases

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086021.1 Reference GRCr8

Range

57287599..57312488 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_008761696.4 → XP_008759918.1 ADP-ribosylation factor-like protein 5A isoform X1

See identical proteins and their annotated locations for XP_008759918.1

UniProtKB/TrEMBL

A6JF25

Conserved Domains (1) summary

cl38936
Location:1 → 138

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases