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Gr64f Gustatory receptor 64f [ Drosophila melanogaster (fruit fly) ]

Gene ID: 117477, updated on 2-Nov-2024

Summary

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Official Symbol
Gr64fprovided by FlyBase
Official Full Name
Gustatory receptor 64fprovided by FlyBase
Primary source
FLYBASE:FBgn0052255
Locus tag
Dmel_CG32255
See related
AllianceGenome:FB:FBgn0052255
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG14988; CG32255; Dmel64f; Dmel\CG32255; DmGr64f; Gr64; Gr64A3; GR64f
Summary
Enables ionotropic sweet taste receptor activity. Involved in detection of chemical stimulus involved in sensory perception of taste and sensory perception of sweet taste. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adult sense organ; adult subesophageal zone; chemosensory neurons; proboscis; and tarsal segment. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See Gr64f in Genome Data Viewer
Location:
64A4-64A4; 3-10 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4035799..4037575)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4035799..4037575)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Gustatory receptor 64c Neighboring gene Gustatory receptor 64b Neighboring gene antisense RNA:CR45042 Neighboring gene Gustatory receptor 64d Neighboring gene Gustatory receptor 64e Neighboring gene uncharacterized protein Neighboring gene Reduction in Cnn dots 5 Neighboring gene Dpy-30-like 2 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Enhancing perception of contaminated food through acid-mediated modulation of taste neuron responses. Chen Y, et al. Curr Biol, 2014 Sep 8. PMID 25131671, Free PMC Article
  2. A subset of sweet-sensing neurons identified by IR56d are necessary and sufficient for fatty acid taste. Tauber JM, et al. PLoS Genet, 2017 Nov. PMID 29121639, Free PMC Article
  3. Drosophila fatty acid taste signals through the PLC pathway in sugar-sensing neurons. Masek P, et al. PLoS Genet, 2013. PMID 24068941, Free PMC Article
  4. Drosophila Gr5a encodes a taste receptor tuned to trehalose. Chyb S, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14523229, Free PMC Article
  5. optoPAD, a closed-loop optogenetics system to study the circuit basis of feeding behaviors. Moreira JM, et al. Elife, 2019 Jun 22. PMID 31226244, Free PMC Article

See all (112) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ionotropic sweet taste receptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables ligand-gated monoatomic ion channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables sweet taste receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables taste receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables taste receptor activity NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of chemical stimulus involved in sensory perception of taste IEA
Inferred from Electronic Annotation
more info
  
involved_in detection of chemical stimulus involved in sensory perception of taste IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in monoatomic ion transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in sensory perception of sweet taste IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sensory perception of sweet taste IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in sensory perception of sweet taste IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sensory perception of taste NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
gustatory receptor 64f
Names
CG32255-PA
Gr64f-PA
gustatory receptor 64A3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    4035799..4037575
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_168052.3 → NP_728924.2  gustatory receptor 64f [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728924.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P83297
    Related
    FBpp0073057
    Conserved Domains (1) summary
    pfam06151
    Location:56 → 462
    Trehalose_recp; Trehalose receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P83297.2 P83297

Gene LinkOut

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