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ARHGEF40 Rho guanine nucleotide exchange factor 40 [ Myotis myotis ]

Gene ID: 118679658, updated on 30-Mar-2024

Summary

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Gene symbol
ARHGEF40
Gene description
Rho guanine nucleotide exchange factor 40
Locus tag
mMyoMyo1_000953
Gene type
protein coding
RefSeq status
MODEL
Organism
Myotis myotis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
Orthologs
human mouse all
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Genomic context

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See ARHGEF40 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
100 current mMyoMyo1.p (GCF_014108235.1) Unplaced Scaffold NW_023416313.1 (149889597..149911956, complement)

NW_023416313.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein SA-like Neighboring gene transmembrane protein 253 Neighboring gene zinc finger protein 219 Neighboring gene uncharacterized LOC118648985 Neighboring gene U6 spliceosomal RNA Neighboring gene ribonuclease A family member 7

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_023416313 Unplaced Scaffold Reference mMyoMyo1.p Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 40

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Myotis myotis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMyoMyo1.p Primary Assembly

Genomic

  1. NW_023416313.1 Reference mMyoMyo1.p Primary Assembly

    Range
    149889597..149911956 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036295546.1 → XP_036151439.1  rho guanine nucleotide exchange factor 40 isoform X5

    UniProtKB/TrEMBL
    A0A7J8AHW9
    Conserved Domains (3) summary
    cd13242
    Location:1254 → 1389
    PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
    cl02488
    Location:786 → 980
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl02571
    Location:1096 → 1255
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  2. XM_036295554.1 → XP_036151447.1  rho guanine nucleotide exchange factor 40 isoform X6

    UniProtKB/TrEMBL
    A0A7J8AHW9
    Conserved Domains (3) summary
    cd13242
    Location:1281 → 1416
    PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
    cl02488
    Location:813 → 1007
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl02571
    Location:1123 → 1282
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  3. XM_036295560.1 → XP_036151453.1  rho guanine nucleotide exchange factor 40 isoform X7

    UniProtKB/TrEMBL
    A0A7J8AHW9
    Conserved Domains (3) summary
    cd13242
    Location:1272 → 1407
    PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
    cl02488
    Location:812 → 998
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl02571
    Location:1114 → 1273
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  4. XM_036295535.1 → XP_036151428.1  rho guanine nucleotide exchange factor 40 isoform X3

    UniProtKB/TrEMBL
    A0A7J8AHW9
    Conserved Domains (3) summary
    cd13242
    Location:1272 → 1407
    PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
    cl02488
    Location:812 → 998
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl02571
    Location:1114 → 1273
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  5. XM_036356677.1 → XP_036212570.1  rho guanine nucleotide exchange factor 40 isoform X2

    UniProtKB/TrEMBL
    A0A7J8AHW9
    Conserved Domains (3) summary
    cd13242
    Location:1281 → 1416
    PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
    cl02488
    Location:813 → 1007
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl02571
    Location:1123 → 1282
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  6. XM_036356669.1 → XP_036212562.1  rho guanine nucleotide exchange factor 40 isoform X1

    UniProtKB/TrEMBL
    A0A7J8AHW9
    Conserved Domains (3) summary
    cd13242
    Location:1281 → 1416
    PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
    cl02488
    Location:813 → 1007
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl02571
    Location:1123 → 1282
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  7. XM_036295539.1 → XP_036151432.1  rho guanine nucleotide exchange factor 40 isoform X4

    UniProtKB/TrEMBL
    A0A7J8AHW9
    Conserved Domains (3) summary
    cd13242
    Location:1272 → 1407
    PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
    cl02488
    Location:812 → 998
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl02571
    Location:1114 → 1273
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
Nucleotide Protein
Heading Accession and Version

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