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Rpl37 ribosomal protein L37 [ Rattus norvegicus (Norway rat) ]

Gene ID: 120093056, updated on 2-Nov-2024

Summary

Official Symbol
Rpl37provided by RGD
Official Full Name
ribosomal protein L37provided by RGD
Primary source
RGD:41394010
See related
EnsemblRapid:ENSRNOG00000064545 AllianceGenome:RGD:41394010
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable MDM2/MDM4 family protein binding activity and ubiquitin ligase inhibitor activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in positive regulation of signal transduction by p53 class mediator. Predicted to be located in cytosolic ribosome. Predicted to be part of cytosolic large ribosomal subunit. Predicted to be active in synapse. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See Rpl37 in Genome Data Viewer
Location:
2q16
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (55942827..55944905)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (54215469..54217429)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene complement C7 Neighboring gene caspase recruitment domain family, member 6 Neighboring gene small nucleolar RNA, C/D box 72 Neighboring gene protein kinase AMP-activated catalytic subunit alpha 1 Neighboring gene small nuclear ribonucleoprotein polypeptide G, pseudogene 5 Neighboring gene tetratricopeptide repeat domain 33

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables MDM2/MDM4 family protein binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
enables ubiquitin ligase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in positive regulation of signal transduction by p53 class mediator ISO
Inferred from Sequence Orthology
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
large ribosomal subunit protein eL37
Names
60S ribosomal protein L37

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399871.1NP_001386800.1  large ribosomal subunit protein eL37

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/Swiss-Prot
    P61928
    UniProtKB/TrEMBL
    A6KGD7
    Related
    ENSRNOP00000083745.2, ENSRNOT00000105106.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    55942827..55944905
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063281201.1XP_063137271.1  large ribosomal subunit protein eL37 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZUB4