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NFKB2 nuclear factor kappa B subunit 2 [ Rana temporaria (common frog) ]

Gene ID: 120947218, updated on 21-Mar-2024

Summary

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Gene symbol
NFKB2
Gene description
nuclear factor kappa B subunit 2
See related
EnsemblRapid:ENSRTEG00010009603
Gene type
protein coding
RefSeq status
MODEL
Organism
Rana temporaria
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana; Rana
Orthologs
human mouse all
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Genomic context

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See NFKB2 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
23
Annotation release Status Assembly Chr Location
100 current aRanTem1.1 (GCF_905171775.1) 8 NC_053496.1 (99895297..99985209, complement)

Chromosome 8 - NC_053496.1Genomic Context describing neighboring genes Neighboring gene F-box and leucine rich repeat protein 15 Neighboring gene pleckstrin and Sec7 domain containing Neighboring gene transmembrane protein 150A-like Neighboring gene golgi brefeldin A resistant guanine nucleotide exchange factor 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_053496.1 Chromosome 8 Reference aRanTem1.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to cytokine IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nuclear factor NF-kappa-B p100 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rana temporaria Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aRanTem1.1

Genomic

  1. NC_053496.1 Reference aRanTem1.1

    Range
    99895297..99985209 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040362363.1 → XP_040218297.1  nuclear factor NF-kappa-B p100 subunit

    Related
    ENSRTEP00010011887.1, ENSRTET00010016109.1
    Conserved Domains (6) summary
    PHA02875
    Location:493 → 667
    PHA02875; ankyrin repeat protein; Provisional
    cd08798
    Location:804 → 878
    Death_NFkB2_p100; Death domain of the Nuclear Factor-KappaB2 precursor protein p100
    smart00248
    Location:670 → 696
    ANK; ankyrin repeats
    cd01177
    Location:230 → 329
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
    sd00045
    Location:605 → 632
    ANK; ANK repeat [structural motif]
    cl08275
    Location:42 → 223
    RHD-n; N-terminal sub-domain of the Rel homology domain (RHD)
Nucleotide Protein
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