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Rps25 ribosomal protein s25 [ Rattus norvegicus (Norway rat) ]

Gene ID: 122799, updated on 2-Nov-2024

Summary

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Official Symbol
Rps25provided by RGD
Official Full Name
ribosomal protein s25provided by RGD
Primary source
RGD:621043
See related
EnsemblRapid:ENSRNOG00000027503 AllianceGenome:RGD:621043
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
A structural constituent of ribosome. Involved in cellular response to amino acid starvation and ribosomal small subunit assembly. Part of cytosolic small ribosomal subunit. Orthologous to human RPS25 (ribosomal protein S25). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 3811.2), Thymus (RPKM 3485.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Rps25 in Genome Data Viewer
Location:
8q22
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (53630333..53632810)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (44733623..44735999)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (48727346..48729722)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 37 member 4 Neighboring gene trafficking protein particle complex subunit 4 Neighboring gene centrosomal AT-AC splicing factor Neighboring gene methyltransferase like 9, pseudogene 1 Neighboring gene forkhead box R1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The primary structure of rat ribosomal protein S25. Chan YL, et al. Biochem Biophys Res Commun, 1992 Aug 14. PMID 1354961
  2. Cloning and sequencing a cDNA encoding human ribosomal protein S25. Li ML, et al. Gene, 1991 Nov 15. PMID 1748303
  3. Nuclear retention of the induced mRNA following amino acid-dependent transcriptional regulation of mammalian ribosomal proteins L17 and S25. Laine RO, et al. J Biol Chem, 1994 Apr 1. PMID 8144559
  4. Nuclear and nucleolar targeting of human ribosomal protein S25: common features shared with HIV-1 regulatory proteins. Kubota S, et al. Oncogene, 1999 Feb 18. PMID 10050887
  5. Ribosomal proteins S2, S6, S10, S14, S15 and S25 are localized on the surface of mammalian 40 S subunits and stabilize their conformation. A study with immobilized trypsin. Marion MJ, et al. FEBS Lett, 1988 May 23. PMID 3378620

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cellular response to amino acid starvation IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in rRNA processing ISO
Inferred from Sequence Orthology
more info
  
involved_in ribosomal small subunit assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
is_active_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome ISO
Inferred from Sequence Orthology
more info
  
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
small ribosomal subunit protein eS25
Names
40S ribosomal protein S25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005528.2 → NP_001005528.1  small ribosomal subunit protein eS25

    See identical proteins and their annotated locations for NP_001005528.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/Swiss-Prot
    P62853, Q3SYP7
    UniProtKB/TrEMBL
    A6J3Z0, F1M6F4
    Related
    ENSRNOP00000033144.7, ENSRNOT00000029546.7
    Conserved Domains (1) summary
    pfam03297
    Location:19 → 111
    Ribosomal_S25; S25 ribosomal protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    53630333..53632810
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063264797.1 → XP_063120867.1  small ribosomal subunit protein eS25 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZLX3
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P62853.1 GenPept UniProtKB/Swiss-Prot:P62853

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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