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CXCL8 C-X-C motif chemokine ligand 8 [ Neogale vison (American mink) ]

Gene ID: 122919291, updated on 22-Mar-2024

Summary

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Gene symbol
CXCL8
Gene description
C-X-C motif chemokine ligand 8
Gene type
protein coding
RefSeq status
MODEL
Organism
Neogale vison
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Neogale
Also known as
IL8
Orthologs
human all
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Genomic context

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See CXCL8 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
4
Annotation release Status Assembly Chr Location
100 current ASM_NN_V1 (GCF_020171115.1) 11 NC_058101.1 (8824387..8827865, complement)

Chromosome 11 - NC_058101.1Genomic Context describing neighboring genes Neighboring gene C-X-C motif chemokine ligand 6 Neighboring gene U6 spliceosomal RNA Neighboring gene Ras association domain family member 6 Neighboring gene alpha-fetoprotein-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_058101.1 Chromosome 11 Reference ASM_NN_V1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables CXCR chemokine receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chemokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in antimicrobial humoral immune response mediated by antimicrobial peptide IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to lipopolysaccharide IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neutrophil chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-8
Names
Interleukin-8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Neovison vison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM_NN_V1 Primary Assembly

Genomic

  1. NC_058101.1 Reference ASM_NN_V1 Primary Assembly

    Range
    8824387..8827865 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044268228.1 → XP_044124163.1  interleukin-8

    UniProtKB/TrEMBL
    U6CS99
    Conserved Domains (1) summary
    cd00273
    Location:31 → 94
    Chemokine_CXC; 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members contain an RCxC motif ...
Nucleotide Protein
Heading Accession and Version

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