U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

HMBS hydroxymethylbilane synthase [ Varanus komodoensis (Komodo dragon) ]

Gene ID: 123036866, updated on 22-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
HMBS
Gene description
hydroxymethylbilane synthase
Locus tag
EYD10_16327
See related
Ensembl:ENSVKKG00000003715
Gene type
protein coding
RefSeq status
MODEL
Organism
Varanus komodoensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Anguimorpha; Paleoanguimorpha; Varanoidea; Varanidae; Varanus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See HMBS in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
100 current ASM479886v1 (GCF_004798865.1) Unplaced Scaffold NW_025336520.1 (68487..77147)

NW_025336520.1Genomic Context describing neighboring genes Neighboring gene hypoxia up-regulated 1 Neighboring gene VPS11 core subunit of CORVET and HOPS complexes Neighboring gene histone H2A-beta, sperm Neighboring gene dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 Neighboring gene C2CD2 like

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_025336520 Unplaced Scaffold Reference ASM479886v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylbilane synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in heme biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-pyrromethane cofactor linkage IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
porphobilinogen deaminase
Names
Porphobilinogen deaminase

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Varanus komodoensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM479886v1

Genomic

  1. NW_025336520.1 Reference ASM479886v1

    Range
    68487..77147
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044456366.1 → XP_044312301.1  porphobilinogen deaminase isoform X1

    UniProtKB/TrEMBL
    A0A8D2KT04
    Conserved Domains (1) summary
    cd13645
    Location:22 → 301
    PBP2_HuPBGD_like; Human porphobilinogen deaminase possess type 2 periplasmic binding protein fold

  2. XM_044456367.1 → XP_044312302.1  porphobilinogen deaminase isoform X2

    UniProtKB/TrEMBL
    A0A8D2IX20, A0A8D2KT04
    Related
    ENSVKKP00000005001.1, ENSVKKT00000005139.1
    Conserved Domains (1) summary
    cd13645
    Location:19 → 298
    PBP2_HuPBGD_like; Human porphobilinogen deaminase possess type 2 periplasmic binding protein fold
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.