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RNF213 ring finger protein 213 [ Varanus komodoensis (Komodo dragon) ]

Gene ID: 123036918, updated on 22-Mar-2024

Summary

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Gene symbol
RNF213
Gene description
ring finger protein 213
Locus tag
EYD10_16393
See related
Ensembl:ENSVKKG00000016407
Gene type
protein coding
RefSeq status
MODEL
Organism
Varanus komodoensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Anguimorpha; Paleoanguimorpha; Varanoidea; Varanidae; Varanus
Orthologs
human mouse all
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Genomic context

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See RNF213 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
69
Annotation release Status Assembly Chr Location
100 current ASM479886v1 (GCF_004798865.1) Unplaced Scaffold NW_025336531.1 (1757890..1893775, complement)

NW_025336531.1Genomic Context describing neighboring genes Neighboring gene neuronal pentraxin 1 Neighboring gene endonuclease V Neighboring gene solute carrier family 26 member 11 Neighboring gene N-sulfoglucosamine sulfohydrolase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_025336531 Unplaced Scaffold Reference ASM479886v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sprouting angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase RNF213

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Varanus komodoensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM479886v1

Genomic

  1. NW_025336531.1 Reference ASM479886v1

    Range
    1757890..1893775 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044456452.1 → XP_044312387.1  E3 ubiquitin-protein ligase RNF213 isoform X3

    UniProtKB/TrEMBL
    A0A8D2LPD7
    Related
    ENSVKKP00000025482.1, ENSVKKT00000026097.1
    Conserved Domains (2) summary
    smart00382
    Location:2380 → 2493
    AAA; ATPases associated with a variety of cellular activities
    cl17238
    Location:3937 → 3976
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  2. XM_044456451.1 → XP_044312386.1  E3 ubiquitin-protein ligase RNF213 isoform X2

    UniProtKB/TrEMBL
    A0A8D2LPD7
    Conserved Domains (2) summary
    smart00382
    Location:2422 → 2535
    AAA; ATPases associated with a variety of cellular activities
    cl17238
    Location:3979 → 4018
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  3. XM_044456450.1 → XP_044312385.1  E3 ubiquitin-protein ligase RNF213 isoform X1

    UniProtKB/TrEMBL
    A0A8D2LPD7
    Conserved Domains (2) summary
    smart00382
    Location:2423 → 2536
    AAA; ATPases associated with a variety of cellular activities
    cl17238
    Location:3980 → 4019
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  4. XM_044456453.1 → XP_044312388.1  E3 ubiquitin-protein ligase RNF213 isoform X4

    UniProtKB/TrEMBL
    A0A8D2LRN9
    Conserved Domains (2) summary
    smart00382
    Location:2423 → 2536
    AAA; ATPases associated with a variety of cellular activities
    cl17238
    Location:3980 → 4019
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
Nucleotide Protein
Heading Accession and Version

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