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Rps23 ribosomal protein S23 [ Rattus norvegicus (Norway rat) ]

Gene ID: 124323, updated on 2-Nov-2024

Summary

Official Symbol
Rps23provided by RGD
Official Full Name
ribosomal protein S23provided by RGD
Primary source
RGD:621039
See related
EnsemblRapid:ENSRNOG00000016580 AllianceGenome:RGD:621039
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal small subunit biogenesis; stress granule assembly; and translation. Part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in brachycephaly, trichomegaly, and developmental delay. Orthologous to human RPS23 (ribosomal protein S23). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 7904.4), Thymus (RPKM 5956.5) and 9 other tissues See more
Orthologs
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Genomic context

See Rps23 in Genome Data Viewer
Location:
2q12
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (23814517..23816087)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (22079339..22080909)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (19823234..19824804)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U109 Neighboring gene transmembrane protein 167A Neighboring gene uncharacterized LOC134485712 Neighboring gene ATPase H+ transporting accessory protein 1 like Neighboring gene autophagy related 10 Neighboring gene uncharacterized LOC120100664 Neighboring gene uncharacterized LOC134485814

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
enables structural constituent of ribosome ISS
Inferred from Sequence or Structural Similarity
more info
 
enables translation regulator activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in cytoplasmic translation IEA
Inferred from Electronic Annotation
more info
 
involved_in cytoplasmic translation ISO
Inferred from Sequence Orthology
more info
 
involved_in cytoplasmic translation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in maintenance of translational fidelity IEA
Inferred from Electronic Annotation
more info
 
involved_in maintenance of translational fidelity ISO
Inferred from Sequence Orthology
more info
 
involved_in maintenance of translational fidelity ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of translation IEA
Inferred from Electronic Annotation
more info
 
involved_in ribosomal small subunit biogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in ribosomal small subunit biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in stress granule assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in stress granule assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in translation ISO
Inferred from Sequence Orthology
more info
 
involved_in translation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in cytoplasmic side of rough endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
 
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
part_of cytosolic small ribosomal subunit IEA
Inferred from Electronic Annotation
more info
 
part_of cytosolic small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
is_active_in ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in ribosome NAS
Non-traceable Author Statement
more info
PubMed 
located_in rough endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
part_of small ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
part_of small-subunit processome IEA
Inferred from Electronic Annotation
more info
 
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
 
part_of small-subunit processome ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
small ribosomal subunit protein uS12
Names
40S ribosomal protein S23

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_078617.3NP_511172.1  small ribosomal subunit protein uS12

    See identical proteins and their annotated locations for NP_511172.1

    Status: PROVISIONAL

    Source sequence(s)
    BC058134
    UniProtKB/Swiss-Prot
    P62268
    UniProtKB/TrEMBL
    A6I4N9
    Related
    ENSRNOP00000022348.6, ENSRNOT00000022348.8
    Conserved Domains (1) summary
    PTZ00067
    Location:1143
    PTZ00067; 40S ribosomal S23; Provisional

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    23814517..23816087
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)