U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LOC126860914 CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:34715861-34717060 [ Homo sapiens (human) ]

Gene ID: 126860914, updated on 10-Oct-2023

Summary

Go to the top of the page Help
Gene symbol
LOC126860914
Gene description
CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:34715861-34717060
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the STARR-seq (self-transcribing active regulatory region sequencing) massively parallel reporter assay in HCT116 colorectal carcinoma cells. This sequence was defined as a group 2 enhancer that depends on the BRD2, BRD4, P300/CBP, MED14 and CDK7 cofactors, with strong dependence on CDK7. [provided by RefSeq, Sep 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 10
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (34426933..34428132)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (34455375..34456574)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2629 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:34318619-34319118 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:34331971-34332472 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:34465469-34465970 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:34471859-34472575 Neighboring gene par-3 family cell polarity regulator Neighboring gene Sharpr-MPRA regulatory region 2386 Neighboring gene tRNA-Leu (CAA) 7-1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:34641233-34641969 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3253 Neighboring gene MPRA-validated peak925 silencer Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:34773554-34774054 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:34774055-34774555 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:34777721-34778257 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:34814928-34815683 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:34817074-34817649 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3254 Neighboring gene elongin B pseudogene 4 Neighboring gene Sharpr-MPRA regulatory region 15357 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3255 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2292 Neighboring gene ribosomal protein L37 pseudogene 18

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_085413.1 

    Range
    101..1300
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    34426933..34428132
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    34455375..34456574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases