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LOC127267608 NANOG-H3K27ac hESC enhancer GRCh37_chr1:15835827-15836756 [ Homo sapiens (human) ]

Gene ID: 127267608, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127267608
Gene description
NANOG-H3K27ac hESC enhancer GRCh37_chr1:15835827-15836756
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor and is marked by the H3K27ac histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127267608 in Genome Data Viewer
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (15509332..15510261)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (14954034..14954963)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (15835827..15836756)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376767 Neighboring gene chymotrypsin like elastase 2A Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:15809342-15809842 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:15809843-15810343 Neighboring gene chymotrypsin like elastase 2B Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:15826802-15827302 Neighboring gene caspase 9 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:15831890-15832390 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 304 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 305 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:15852999-15853502 Neighboring gene Sharpr-MPRA regulatory region 4011 Neighboring gene DnaJ heat shock protein family (Hsp40) member C16 Neighboring gene small Cajal body-specific RNA 21B Neighboring gene ATAC-STARR-seq lymphoblastoid active region 239 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 308 Neighboring gene agmatinase (putative)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_089483.1 

    Range
    101..1030
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    15509332..15510261
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    14954034..14954963
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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