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LOC127267741 H3K4me1 hESC enhancer GRCh37_chr1:17300945-17301752 [ Homo sapiens (human) ]

Gene ID: 127267741, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127267741
Gene description
H3K4me1 hESC enhancer GRCh37_chr1:17300945-17301752
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127267741 in Genome Data Viewer
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (16974450..16975257)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (16784877..16785684)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (17300945..17301752)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:17221837-17222770 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:17222771-17223703 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 271 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:17230789-17231428 Neighboring gene Sharpr-MPRA regulatory region 252 Neighboring gene RNA, U1 small nuclear 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 337 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:17247068-17247840 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:17247841-17248612 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:17248613-17249384 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17249385-17250156 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17250340-17250950 Neighboring gene ciliary rootlet coiled-coil, rootletin Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17252780-17253390 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:17259505-17259699 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 338 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:17298533-17299510 Neighboring gene uncharacterized LOC105376806 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17304877-17305382 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17305383-17305890 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17305891-17306396 Neighboring gene microfibril associated protein 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:17319735-17320236 Neighboring gene ATPase cation transporting 13A2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 274 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 275 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 339

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_089602.1 

    Range
    101..908
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    16974450..16975257
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791756.1 Reference GRCh38.p14 PATCHES

    Range
    1389624..1390431
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    16784877..16785684
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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