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LOC127269211 H3K4me1 hESC enhancer GRCh37_chr1:53580852-53581834 [ Homo sapiens (human) ]

Gene ID: 127269211, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127269211
Gene description
H3K4me1 hESC enhancer GRCh37_chr1:53580852-53581834
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127269211 in Genome Data Viewer
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (53115180..53116162)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (52996599..52997581)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (53580852..53581834)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene sterol carrier protein 2 Neighboring gene tubulin beta class I pseudogene 10 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1040 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:53527863-53528050 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:53546830-53547381 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:53547382-53547932 Neighboring gene HIG1 hypoxia inducible domain family member 1A pseudogene 11 Neighboring gene podocan Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:53560558-53561095 Neighboring gene H3K4me1 hESC enhancers GRCh37_chr1:53571119-53571620 and GRCh37_chr1:53571621-53572120 Neighboring gene Sharpr-MPRA regulatory region 13647 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:53576791-53577515 Neighboring gene solute carrier family 1 member 7 Neighboring gene uncharacterized LOC105379783 Neighboring gene VISTA enhancer hs2585 Neighboring gene uncharacterized LOC105378724 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1041 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 902 Neighboring gene MPRA-validated peak232 silencer Neighboring gene carnitine palmitoyltransferase 2 pseudogene 1 Neighboring gene carnitine palmitoyltransferase 2 Neighboring gene CXXC motif containing zinc binding protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_091072.1 

    Range
    101..1083
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    53115180..53116162
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    52996599..52997581
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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