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LOC127271377 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:205657475-205658431 [ Homo sapiens (human) ]

Gene ID: 127271377, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127271377
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:205657475-205658431
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127271377 in Genome Data Viewer
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (205688347..205689303)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (204953010..204953969)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (205657475..205658431)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene GABA type A receptor-associated protein pseudogene Neighboring gene ETS transcription factor ELK4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2383 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2384 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1745 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1746 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2385 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:205629205-205629793 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:205631113-205631667 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:205631668-205632223 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr1:205633133-205634332 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2386 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2387 Neighboring gene solute carrier family 45 member 3 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:205639145-205639706 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:205644516-205645016 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:205645017-205645517 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_1682 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1747 Neighboring gene uncharacterized LOC105371701 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:205662277-205662826 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:205670015-205670516 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:205670517-205671016 Neighboring gene nuclear casein kinase and cyclin dependent kinase substrate 1 Neighboring gene small nucleolar RNA SNORA72 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:205708952-205709557 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:205709558-205710164 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:205711268-205711871 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:205711872-205712474 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1748 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2388 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2389 Neighboring gene RAB29, member RAS oncogene family

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_093229.1 

    Range
    101..1057
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    205688347..205689303
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    204953010..204953969
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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