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LOC127271646 NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:223195995-223196670 [ Homo sapiens (human) ]

Gene ID: 127271646, updated on 27-Aug-2024

Summary

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Gene symbol
LOC127271646
Gene description
NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:223195995-223196670
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor and is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (223022653..223023328)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (222256516..222257191)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene dispatched RND transporter family member 1 Neighboring gene small nucleolar RNA U13 Neighboring gene NADH:ubiquinone oxidoreductase subunit B1 pseudogene 2 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:223197347-223198022 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:223198023-223198698 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr1:223198699-223199373 Neighboring gene 1q41-q42 HERV-mediated distal recombination region Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr1:223199517-223200274 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:223202549-223203306 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:223203307-223204064 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:223204065-223204822 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:223209992-223210672 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:223211353-223212032 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:223226073-223226573 Neighboring gene uncharacterized LOC124904520 Neighboring gene uncharacterized LOC124904521

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_093498.1 

    Range
    101..776
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    223022653..223023328
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    222256516..222257191
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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