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LOC127272012 NANOG hESC enhancer GRCh37_chr1:233813209-233813831 [ Homo sapiens (human) ]

Gene ID: 127272012, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127272012
Gene description
NANOG hESC enhancer GRCh37_chr1:233813209-233813831
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127272012 in Genome Data Viewer
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (233677463..233678085)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (233063922..233064544)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (233813209..233813831)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene RNA, U4 small nuclear 77, pseudogene Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr1:233606496-233607383 Neighboring gene Sharpr-MPRA regulatory region 5532 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:233710261-233710483 Neighboring gene NANOG hESC enhancer GRCh37_chr1:233723731-233724591 Neighboring gene NANOG hESC enhancer GRCh37_chr1:233737273-233737774 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2742 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:233748978-233749630 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1964 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1965 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2743 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2744 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr1:233771758-233772307 Neighboring gene potassium two pore domain channel subfamily K member 1 Neighboring gene microRNA 4427 Neighboring gene NANOG hESC enhancer GRCh37_chr1:233814980-233815481 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr1:233824287-233825116 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:233825117-233825946 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:233825947-233826776 Neighboring gene uncharacterized LOC107985362 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr1:233843943-233845142 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr1:233859728-233860927 Neighboring gene uncharacterized LOC124904552 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:233865794-233866564 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:233866565-233867336

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_093863.1 

    Range
    101..723
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    233677463..233678085
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    233063922..233064544
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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