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LOC127272057 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:235245875-235246397 [ Homo sapiens (human) ]

Gene ID: 127272057, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127272057
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:235245875-235246397
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127272057 in Genome Data Viewer
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (235082560..235083082)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (234474286..234474808)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:235115282-235115785 Neighboring gene long intergenic non-protein coding RNA 3108 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancers GRCh37_chr1:235122747-235123286 and GRCh37_chr1:235122207-235122746 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:235123287-235123826 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:235133684-235134883 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2780 Neighboring gene Sharpr-MPRA regulatory region 4658 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2784 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2785 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2786 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2787 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2788 Neighboring gene Sharpr-MPRA regulatory region 5019 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2789 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:235191005-235191504 Neighboring gene long intergenic non-protein coding RNA 1348 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2790 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:235256647-235257230 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2791 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1984 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2792 Neighboring gene translocase of outer mitochondrial membrane 20 Neighboring gene uncharacterized LOC105379283 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2793 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2794 Neighboring gene small nucleolar RNA, H/ACA box 14B Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2795 Neighboring gene RNA binding motif protein 34 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:235322928-235323532 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr1:235323819-235325018

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_093908.1 

    Range
    101..623
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    235082560..235083082
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    234474286..234474808
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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