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LOC127272477 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8777331-8777854 [ Homo sapiens (human) ]

Gene ID: 127272477, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127272477
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8777331-8777854
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127272477 in Genome Data Viewer
Location:
chromosome: 2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (8637201..8637724)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (8660867..8661390)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (8777331..8777854)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 1814 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8712051-8712630 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15270 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15271 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15272 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8723860-8724539 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8724540-8725218 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:8727462-8728114 Neighboring gene uncharacterized LOC105373411 Neighboring gene SNRPE pseudogene 5 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:8773308-8774507 Neighboring gene VISTA enhancer hs1527 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr2:8802380-8803579 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8815873-8816791 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8816792-8817709 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:8818423-8818956 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8818957-8819490 Neighboring gene ID2 antisense RNA 1 Neighboring gene NANOG hESC enhancer GRCh37_chr2:8821385-8821888 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15273 Neighboring gene inhibitor of DNA binding 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_094328.1 

    Range
    101..624
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    8637201..8637724
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    8660867..8661390
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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