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LOC127275676 NANOG hESC enhancer GRCh37_chr2:211307490-211308075 [ Homo sapiens (human) ]

Gene ID: 127275676, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127275676
Gene description
NANOG hESC enhancer GRCh37_chr2:211307490-211308075
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127275676 in Genome Data Viewer
Location:
chromosome: 2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (210442766..210443351)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (210923542..210924127)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (211307490..211308075)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124907972 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:211111447-211112014 Neighboring gene LANCL1 antisense RNA 1 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr2:211225248-211226447 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:211229754-211230953 Neighboring gene myosin light chain 1 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr2:211294046-211295245 Neighboring gene NANOG hESC enhancer GRCh37_chr2:211346110-211346611 Neighboring gene LanC like glutathione S-transferase 1 Neighboring gene NANOG hESC enhancer GRCh37_chr2:211405459-211406038 Neighboring gene CPS1 intron CAGE-defined high expression enhancer 1 Neighboring gene CPS1 intron CAGE-defined high expression enhancer 2 Neighboring gene carbamoyl-phosphate synthase 1 Neighboring gene CPS1 intronic transcript 1 Neighboring gene uncharacterized LOC107985978

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_097524.1 

    Range
    101..686
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    210442766..210443351
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    210923542..210924127
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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