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LOC127397276 H3K4me1 hESC enhancer GRCh37_chr3:46497203-46497704 [ Homo sapiens (human) ]

Gene ID: 127397276, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127397276
Gene description
H3K4me1 hESC enhancer GRCh37_chr3:46497203-46497704
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
Annotation information
Note: This locus has been reviewed for its involvement in coronavirus biology, and is regulatory element in the vicinity of coronavirus related gene(s).
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Genomic context

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See LOC127397276 in Genome Data Viewer
Location:
chromosome: 3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (46455713..46456214)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (46471547..46472048)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (46497203..46497704)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene C-C motif chemokine receptor like 2 Neighboring gene long intergenic non-protein coding RNA 2009 Neighboring gene Sharpr-MPRA regulatory region 12992 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:46484307-46484808 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:46491889-46492388 Neighboring gene lactotransferrin Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:46497705-46498204 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:46511713-46512212 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:46519415-46519916 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:46519917-46520416 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:46530070-46530846 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:46530847-46531621 Neighboring gene receptor transporter protein 3 Neighboring gene Sharpr-MPRA regulatory region 6156 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr3:46561999-46563198 Neighboring gene leucine rich repeat containing 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19797 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:46585952-46586496 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:46598181-46598782 Neighboring gene LRRC2 antisense RNA 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_099245.1 

    Range
    101..602
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    46455713..46456214
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    46471547..46472048
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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