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LOC127398464 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124493806-124494521 [ Homo sapiens (human) ]

Gene ID: 127398464, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127398464
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124493806-124494521
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127398464 in Genome Data Viewer
Location:
chromosome: 3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (124774959..124775674)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (127500813..127501522)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (124493806..124494521)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene ribosomal protein S26 pseudogene 22 Neighboring gene microRNA 544b Neighboring gene uridine monophosphate synthetase Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr3:124469851-124470517 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr3:124475893-124476862 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124478413-124479002 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124479003-124479592 Neighboring gene Sharpr-MPRA regulatory region 9344 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14654 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20403 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124490944-124491659 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124491660-124492374 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124493091-124493805 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124495953-124496666 Neighboring gene integrin subunit beta 5 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20404 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20405 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:124509941-124510473 Neighboring gene uncharacterized LOC124909422 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124531305-124531909 Neighboring gene uncharacterized LOC124906277 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:124545465-124546128 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr3:124546129-124546792

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_100433.1 

    Range
    101..816
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    124774959..124775674
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    127500813..127501522
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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