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LOC127399917 H3K4me1 hESC enhancer GRCh37_chr4:3483446-3484412 [ Homo sapiens (human) ]

Gene ID: 127399917, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127399917
Gene description
H3K4me1 hESC enhancer GRCh37_chr4:3483446-3484412
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127399917 in Genome Data Viewer
Location:
chromosome: 4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (3481719..3482685)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (3481505..3482471)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (3483446..3484412)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene regulator of G protein signaling 12 Neighboring gene ribosomal protein L7a pseudogene 29 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3374529-3375457 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21222 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21223 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21224 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3411075-3411982 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr4:3417810-3419009 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3422145-3422646 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3425913-3426412 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3434795-3435296 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3435297-3435796 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3436172-3437070 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3437071-3437969 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3438515-3439015 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15205 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3450782-3451585 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:3463811-3464658 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3467576-3468185 Neighboring gene HGF activator Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3469405-3470012 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:3474943-3475654 Neighboring gene ReSE screen-validated silencer GRCh37_chr4:3476364-3476557 Neighboring gene vegetative cell wall protein gp1-like Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3481667-3482258 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr4:3482478-3483445 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr4:3486115-3487314 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:3487316-3488282 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15206 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:3494329-3494850 Neighboring gene docking protein 7 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr4:3510576-3511775 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr4:3516456-3517655 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3517921-3518540 Neighboring gene LDL receptor related protein associated protein 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3528991-3529881 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:3529882-3530771 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15207 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21225 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15208 Neighboring gene uncharacterized LOC124900650

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_101881.1 

    Range
    101..1067
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    3481719..3482685
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    3481505..3482471
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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