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LOC127401092 NANOG hESC enhancer GRCh37_chr4:84917176-84917884 [ Homo sapiens (human) ]

Gene ID: 127401092, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127401092
Gene description
NANOG hESC enhancer GRCh37_chr4:84917176-84917884
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127401092 in Genome Data Viewer
Location:
chromosome: 4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (83996023..83996731)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (87325947..87326655)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (84917176..84917884)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr4:84469077-84470276 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15543 Neighboring gene Sharpr-MPRA regulatory region 7334 Neighboring gene glycerol-3-phosphate acyltransferase 3 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr4:84539256-84540455 Neighboring gene Sharpr-MPRA regulatory region 4612 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:84557857-84558358 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21689 Neighboring gene VISTA enhancer hs712 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:84702313-84703031 Neighboring gene uncharacterized LOC105377315 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:84771005-84771616 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:84771617-84772228 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr4:84775825-84777024 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:84843248-84843790 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:84843791-84844331 Neighboring gene long intergenic non-protein coding RNA 2994 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:85048206-85048769 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:85165003-85165976 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:85165977-85166950 Neighboring gene RNA, U6 small nuclear 774, pseudogene Neighboring gene PLAG1 like zinc finger 2 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_103055.1 

    Range
    101..809
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    83996023..83996731
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    87325947..87326655
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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