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LOC127403177 OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:76618089-76618784 [ Homo sapiens (human) ]

Gene ID: 127403177, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127403177
Gene description
OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:76618089-76618784
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors and is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127403177 in Genome Data Viewer
Location:
chromosome: 5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (77322264..77322959)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (77804176..77804869)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (76618089..76618784)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene ZBED3 antisense RNA 1 Neighboring gene phosphodiesterase 8B Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:76468397-76468898 Neighboring gene high mobility group box 1 pseudogene 35 Neighboring gene aldehyde dehydrogenase 7 family member A1 pseudogene 1 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr5:76672412-76673040 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:76752518-76752693 Neighboring gene WD repeat domain 41 Neighboring gene uncharacterized LOC124901009 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:76787603-76788526 Neighboring gene ribosomal protein S2 pseudogene 24

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_105126.1 

    Range
    101..796
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    77322264..77322959
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    77804176..77804869
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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