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LOC127403632 OCT4-NANOG hESC enhancer GRCh37_chr5:118794469-118795121 [ Homo sapiens (human) ]

Gene ID: 127403632, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127403632
Gene description
OCT4-NANOG hESC enhancer GRCh37_chr5:118794469-118795121
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127403632 in Genome Data Viewer
Location:
chromosome: 5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (119458774..119459426)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (119979616..119980268)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene TNF alpha induced protein 8 Neighboring gene uncharacterized LOC102723444 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22974 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22975 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22976 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22977 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22978 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16265 Neighboring gene Sharpr-MPRA regulatory region 6110 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22979 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22980 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22981 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22982 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22983 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:118726761-118726918 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22984 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22986 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22985 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr5:118737716-118738284 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:118740092-118740592 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22987 Neighboring gene Sharpr-MPRA regulatory region 10011 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22989 Neighboring gene RNA, 5S ribosomal pseudogene 190 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:118797267-118797484 Neighboring gene uncharacterized LOC124901215 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:118805521-118806252 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:118806253-118806984 Neighboring gene hydroxysteroid 17-beta dehydrogenase 4 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr5:118815935-118816518 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr5:118816519-118817102 Neighboring gene Sharpr-MPRA regulatory region 15152 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22990 Neighboring gene ribosomal protein L21 pseudogene 58

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_105581.1 

    Range
    101..753
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    119458774..119459426
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    119979616..119980268
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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