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LOC127403969 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:137946542-137947174 [ Homo sapiens (human) ]

Gene ID: 127403969, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127403969
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:137946542-137947174
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127403969 in Genome Data Viewer
Location:
chromosome: 5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (138610853..138611485)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (139137072..139137704)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (137946542..137947174)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105379193 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:137910671-137911318 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:137911319-137911967 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23210 Neighboring gene small nucleolar RNA, C/D box 63 Neighboring gene heat shock protein family A (Hsp70) member 9 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23211 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23212 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:137945276-137945908 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:137945909-137946541 Neighboring gene small nucleolar RNA U13 Neighboring gene ribosomal protein L10a pseudogene 10 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:137976937-137977490 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:137977491-137978044 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:137986181-137986979 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:138001425-138001925 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16402 Neighboring gene Sharpr-MPRA regulatory region 9755 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16403 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23215 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:138089147-138089714 Neighboring gene CTNNA1 antisense RNA 1 Neighboring gene catenin alpha 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_105918.1 

    Range
    101..733
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    138610853..138611485
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    139137072..139137704
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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