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LOC127404804 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:176075745-176076614 [ Homo sapiens (human) ]

Gene ID: 127404804, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127404804
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:176075745-176076614
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127404804 in Genome Data Viewer
Location:
chromosome: 5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (176648744..176649613)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (177195332..177196201)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (176075745..176076614)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16663 Neighboring gene synuclein beta Neighboring gene microRNA 4281 Neighboring gene eukaryotic translation initiation factor 4E family member 1B Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:176070445-176071086 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:176071087-176071726 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:176072308-176072818 Neighboring gene Sharpr-MPRA regulatory region 4950 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16664 Neighboring gene VISTA enhancer hs2007 Neighboring gene tetraspanin 17 Neighboring gene uncharacterized LOC124901144 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:176087757-176088480 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:176093385-176093611 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:176098601-176099166 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr5:176099167-176099730 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:176106874-176107834 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:176107835-176108794 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:176119741-176120285 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:176124309-176125132 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:176126779-176127601 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:176139283-176140243 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:176148139-176148638 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:176152218-176152749 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:176152750-176153280 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:176159360-176160290 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:176160291-176161220 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:176167545-176168254 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:176170772-176171740 Neighboring gene long intergenic non-protein coding RNA 1574

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_106749.1 

    Range
    101..970
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    176648744..176649613
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    177195332..177196201
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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