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LOC127404979 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:178956772-178957378 [ Homo sapiens (human) ]

Gene ID: 127404979, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127404979
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:178956772-178957378
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127404979 in Genome Data Viewer
Location:
chromosome: 5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (179529771..179530377)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (180082368..180082974)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (178956772..178957378)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100128622 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16729 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:178941125-178941972 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:178945330-178946105 Neighboring gene uncharacterized LOC128966623 Neighboring gene chromosome 5 open reading frame 60-like Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:178957379-178957984 Neighboring gene uncharacterized LOC105377762 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23750 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16730 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:178981435-178981935 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:178982640-178982816 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23751 Neighboring gene RUN and FYVE domain containing 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:178998880-178999380 Neighboring gene peroxiredoxin 2 pseudogene 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_106924.1 

    Range
    101..707
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    179529771..179530377
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_016107298.1 Reference GRCh38.p14 PATCHES

    Range
    294275..294881
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    180082368..180082974
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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