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LOC127407665 H3K27ac hESC enhancer GRCh37_chr6:159030351-159030852 [ Homo sapiens (human) ]

Gene ID: 127407665, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127407665
Gene description
H3K27ac hESC enhancer GRCh37_chr6:159030351-159030852
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127407665 in Genome Data Viewer
Location:
chromosome: 6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (158609319..158609820)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (159854495..159854996)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (159030351..159030852)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene TUB like protein 4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25355 Neighboring gene RNA, 7SL, cytoplasmic 173, pseudogene Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:158884819-158885810 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:158885811-158886802 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:158890813-158891694 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:158895792-158896364 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25358 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25357 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25356 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:158900383-158900884 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:158927517-158928017 Neighboring gene Sharpr-MPRA regulatory region 4140 Neighboring gene Sharpr-MPRA regulatory region 10808 Neighboring gene calcyclin binding protein pseudogene 3 Neighboring gene Sharpr-MPRA regulatory region 807 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17739 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:158982655-158983154 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:158982153-158982654 Neighboring gene transmembrane protein 181 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:159000120-159000332 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:159051575-159052076 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:159052077-159052576 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:159053255-159053416 Neighboring gene TatD DNase domain containing 2 pseudogene 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:159065146-159066089 Neighboring gene microRNA 7161 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17742 Neighboring gene dynein light chain Tctex-type 1 Neighboring gene MPRA-validated peak6273 silencer Neighboring gene synaptotagmin like 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25359 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:159128779-159129410 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:159129411-159130042 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25360 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr6:159141094-159142293 Neighboring gene AMZ2 pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_109635.1 

    Range
    101..602
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    158609319..158609820
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    159854495..159854996
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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