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LOC127407817 NANOG hESC enhancer GRCh37_chr6:166965189-166965763 [ Homo sapiens (human) ]

Gene ID: 127407817, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127407817
Gene description
NANOG hESC enhancer GRCh37_chr6:166965189-166965763
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127407817 in Genome Data Viewer
Location:
chromosome: 6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (166551701..166552275)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (167929198..167929772)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (166965189..166965763)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene ribosomal protein S6 kinase A2 Neighboring gene RPS6KA2 intronic transcript 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:166883011-166883914 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:166883915-166884818 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:166889542-166890188 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:166899351-166899851 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:166903150-166903650 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:166908262-166908949 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr6:166917274-166918473 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:166919624-166920564 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:166920565-166921504 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:166946507-166947008 Neighboring gene microRNA 1913 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25435 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25436 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr6:166955818-166956418 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:166956766-166957686 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:166978541-166979078 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:166985773-166986662 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:166993250-166993750 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:166993751-166994251 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:166994332-166995152 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17778 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25437 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25438 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:167032008-167032774 Neighboring gene RNA guanine-7 methyltransferase activating subunit like Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr6:167034435-167034935 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17779 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17780 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17781 Neighboring gene uncharacterized LOC107986671

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_109787.1 

    Range
    101..675
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    166551701..166552275
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    167929198..167929772
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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