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LOC127408612 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:22704600-22705208 [ Homo sapiens (human) ]

Gene ID: 127408612, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127408612
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:22704600-22705208
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127408612 in Genome Data Viewer
Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (22664981..22665589)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (22800856..22801464)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (22704600..22705208)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene 6 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:22602981-22603482 Neighboring gene STEAP1B antisense RNA 1 Neighboring gene CAGE-defined low expression enhancer in LOC100506178-LOC401312 intergenic region Neighboring gene uncharacterized LOC401312 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:22703992-22704599 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:22705209-22705815 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:22708433-22709061 Neighboring gene Sharpr-MPRA regulatory region 4516 Neighboring gene CRISPRi-validated cis-regulatory element chr7.1154 Neighboring gene CRISPRi-validated cis-regulatory element chr7.1155 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:22748460-22749096 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18003 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr7:22766269-22767468 Neighboring gene IL6 antisense RNA 1 Neighboring gene interleukin 6 Neighboring gene MT-CYB pseudogene 42

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_110580.1 

    Range
    101..709
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    22664981..22665589
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    22800856..22801464
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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