U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LOC127408959 OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:42261657-42262165 [ Homo sapiens (human) ]

Gene ID: 127408959, updated on 12-Sep-2024

Summary

Gene symbol
LOC127408959
Gene description
OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:42261657-42262165
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors and is marked by the H3K27ac histone modification. [provided by RefSeq, Oct 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See LOC127408959 in Genome Data Viewer
Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (42222058..42222566)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (42380362..42380870)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (42261657..42262165)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124901618 Neighboring gene GLI family zinc finger 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:42068797-42069297 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:42105443-42106096 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:42131129-42131824 Neighboring gene NANOG hESC enhancer GRCh37_chr7:42178252-42178762 Neighboring gene high mobility group nucleosomal binding domain 2 pseudogene 30 Neighboring gene VISTA enhancer hs1586 Neighboring gene VISTA enhancer hs111 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr7:42232601-42233188 Neighboring gene VISTA enhancer hs1213 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:42267911-42268690 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:42276552-42277533 Neighboring gene uncharacterized LOC105375249 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:42376548-42377052 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:42377053-42377557 Neighboring gene Sharpr-MPRA regulatory region 1141 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr7:42410696-42411895 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:42533107-42533607 Neighboring gene uncharacterized LOC105375250

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_110925.1 

    Range
    101..609
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    42222058..42222566
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    42380362..42380870
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)