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LOC127409375 H3K4me1 hESC enhancer GRCh37_chr7:66131083-66131823 [ Homo sapiens (human) ]

Gene ID: 127409375, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127409375
Gene description
H3K4me1 hESC enhancer GRCh37_chr7:66131083-66131823
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127409375 in Genome Data Viewer
Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (66666096..66666836)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (67885760..67886500)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (66131083..66131823)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene ribosomal protein L35 pseudogene 5 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18209 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18210 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26084 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26085 Neighboring gene potassium channel tetramerization domain containing 7 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:66118787-66119392 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:66119393-66119998 Neighboring gene uncharacterized LOC100996437 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:66119999-66120604 Neighboring gene MPRA-validated peak6548 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:66131824-66132563 Neighboring gene RAB guanine nucleotide exchange factor 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:66146939-66147678 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:66157983-66158483 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:66161889-66162390 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:66192681-66193181 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26086 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:66205397-66206063 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26087 Neighboring gene uncharacterized LOC107986707 Neighboring gene GrpE like 1, mitochondrial pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_111340.1 

    Range
    101..841
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    66666096..66666836
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    67885760..67886500
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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