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LOC127456838 H3K27ac hESC enhancer GRCh37_chr7:76586180-76587044 [ Homo sapiens (human) ]

Gene ID: 127456838, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127456838
Gene description
H3K27ac hESC enhancer GRCh37_chr7:76586180-76587044
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127456838 in Genome Data Viewer
Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (76956863..76957727)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (78235764..78236629)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (76586180..76587044)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 3009 Neighboring gene 7q11.23 distal recombination region Neighboring gene ReSE screen-validated silencer GRCh37_chr7:76261368-76261573 Neighboring gene POM121 and ZP3 fusion Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:76302620-76303188 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr7:76357185-76358384 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:76513437-76513979 Neighboring gene uncharacterized LOC105375358 Neighboring gene DTX2P1-UPK3BP1-PMS2P11 readthrough, transcribed pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:76583582-76584448 Neighboring gene MPRA-validated peak6614 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:76612883-76613456 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26202 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:76628288-76629118 Neighboring gene DTX2 pseudogene 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:76629119-76629947 Neighboring gene farnesyl diphosphate synthase pseudogene 7 Neighboring gene uroplakin 3B pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_111613.1 

    Range
    101..965
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    76956863..76957727
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    78235764..78236629
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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