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LOC127457504 NANOG hESC enhancer GRCh37_chr7:120422555-120423072 [ Homo sapiens (human) ]

Gene ID: 127457504, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127457504
Gene description
NANOG hESC enhancer GRCh37_chr7:120422555-120423072
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127457504 in Genome Data Viewer
Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (120782501..120783018)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (122097830..122098347)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (120422555..120423072)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375477 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:119896333-119897012 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:119897013-119897691 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18570 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18571 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26550 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26551 Neighboring gene potassium voltage-gated channel subfamily D member 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26552 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26553 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26554 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:120142038-120142659 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:120162507-120163318 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:120161695-120162506 Neighboring gene RNA, U6 small nuclear 581, pseudogene Neighboring gene Sharpr-MPRA regulatory region 15278 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18572 Neighboring gene tetraspanin 12 Neighboring gene uncharacterized LOC124901733 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:120497141-120497360 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18573 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:120508165-120508289 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26555 Neighboring gene uncharacterized LOC124901734 Neighboring gene inhibitor of growth family member 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_112278.1 

    Range
    101..618
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    120782501..120783018
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    122097830..122098347
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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