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LOC127458626 H3K4me1 hESC enhancer GRCh37_chr8:10273265-10274127 [ Homo sapiens (human) ]

Gene ID: 127458626, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127458626
Gene description
H3K4me1 hESC enhancer GRCh37_chr8:10273265-10274127
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127458626 in Genome Data Viewer
Location:
chromosome: 8
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (10415755..10416617)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (9322599..9323461, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene methionine sulfoxide reductase A Neighboring gene uncharacterized LOC124901886 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26989 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:10109393-10109588 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26990 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26991 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:10191156-10191980 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:10191981-10192805 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr8:10194133-10194989 Neighboring gene transmembrane protein 126A pseudogene Neighboring gene ReSE screen-validated silencer GRCh37_chr8:10214030-10214233 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr8:10275622-10276144 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:10280427-10280927 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:10282861-10283372 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:10283373-10283882 Neighboring gene uncharacterized LOC124901887 Neighboring gene long intergenic non-protein coding RNA 3022 Neighboring gene RNA, U6 small nuclear 729, pseudogene Neighboring gene serine protease 52, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_113395.1 

    Range
    101..963
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    10415755..10416617
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_018654717.1 Reference GRCh38.p14 PATCHES

    Range
    2930447..2931309 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    9322599..9323461 complement
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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