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LOC127459458 H3K4me1 hESC enhancer GRCh37_chr8:49091903-49092402 [ Homo sapiens (human) ]

Gene ID: 127459458, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127459458
Gene description
H3K4me1 hESC enhancer GRCh37_chr8:49091903-49092402
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127459458 in Genome Data Viewer
Location:
chromosome: 8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (48179343..48179842)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (48557205..48557703)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (49091903..49092402)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene UBE2V2 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19180 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19181 Neighboring gene ubiquitin conjugating enzyme E2 V2 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:48947276-48947776 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:48947777-48948277 Neighboring gene MPRA-validated peak7010 silencer Neighboring gene uncharacterized LOC107986941 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:49017963-49018613 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:49042982-49043566 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:49091401-49091902 Neighboring gene cell division cycle associated 8 pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:49111559-49112066 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:49112067-49112573 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr8:49166365-49167210 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:49173243-49173804 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr8:49173820-49174820 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:49183073-49183944 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:49186311-49186812 Neighboring gene IDI1 pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_114227.1 

    Range
    101..600
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    48179343..48179842
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791782.1 Reference GRCh38.p14 PATCHES

    Range
    114993..115492
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    48557205..48557703
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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