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LOC127460363 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:130882553-130883105 [ Homo sapiens (human) ]

Gene ID: 127460363, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127460363
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:130882553-130883105
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127460363 in Genome Data Viewer
Location:
chromosome: 8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (129870307..129870859)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (130996270..130996822)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (130882553..130883105)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene CYFIP related Rac1 interactor B Neighboring gene uncharacterized LOC124900265 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:130881998-130882552 Neighboring gene ribosomal protein L15 pseudogene 12 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:130899091-130899604 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:130899605-130900116 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27971 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27972 Neighboring gene MPRA-validated peak7177 silencer Neighboring gene Sharpr-MPRA regulatory region 603 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19541 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27973 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:130957594-130958094 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:130971367-130971867 Neighboring gene MPRA-validated peak7178 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27974 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27975 Neighboring gene uncharacterized LOC124902025 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27976 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:131005193-131005693 Neighboring gene RNA, U7 small nuclear 181 pseudogene Neighboring gene microRNA 5194

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_115132.1 

    Range
    101..653
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    129870307..129870859
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    130996270..130996822
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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