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LOC127814685 OCT4-NANOG hESC enhancer GRCh37_chr9:35157812-35158365 [ Homo sapiens (human) ]

Gene ID: 127814685, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127814685
Gene description
OCT4-NANOG hESC enhancer GRCh37_chr9:35157812-35158365
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127814685 in Genome Data Viewer
Location:
chromosome: 9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (35157815..35158368)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (35177018..35177571)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (35157812..35158365)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124902147 Neighboring gene zinc finger protein 492 pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19863 Neighboring gene unc-13 homolog B Neighboring gene Sharpr-MPRA regulatory region 3537 Neighboring gene MPRA-validated peak7230 silencer Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr9:35327315-35328514 Neighboring gene Sharpr-MPRA regulatory region 14419 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr9:35373268-35373820 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr9:35397379-35398578 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr9:35403221-35404420 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:35405745-35406290 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr9:35406291-35406836 Neighboring gene ATPase phospholipid transporting 8B5, pseudogene Neighboring gene zinc finger AN1-type containing 6 pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_116205.1 

    Range
    101..654
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    35157815..35158368
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    35177018..35177571
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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