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LOC127815321 NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:97316904-97317566 [ Homo sapiens (human) ]

Gene ID: 127815321, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127815321
Gene description
NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:97316904-97317566
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor and is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127815321 in Genome Data Viewer
Location:
chromosome: 9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (94554622..94555284)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (106723946..106724608)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (97316904..97317566)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain containing 14B Neighboring gene yrdC N(6)-threonylcarbamoyltransferase domain containing pseudogene 1 Neighboring gene MPRA-validated peak7296 silencer Neighboring gene uncharacterized LOC107987100 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_110230 Neighboring gene MPRA-validated peak7297 silencer Neighboring gene leishmanolysin like peptidase pseudogene Neighboring gene RNA, U6 small nuclear 669, pseudogene Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_110244 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_110264 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_110288 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_110294 Neighboring gene uncharacterized LOC124902218 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:97315577-97316239 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:97320892-97321392 Neighboring gene prostate cancer associated transcript 7 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:97349793-97350294 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:97350295-97350794 Neighboring gene fructose-bisphosphatase 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:97353573-97354115 Neighboring gene NANOG hESC enhancer GRCh37_chr9:97370327-97370828 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:97372257-97372756 Neighboring gene fructose-bisphosphatase 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20057

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_116837.1 

    Range
    101..763
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    94554622..94555284
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    106723946..106724608
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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