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LOC127817183 H3K27ac hESC enhancer GRCh37_chr10:7407161-7407660 [ Homo sapiens (human) ]

Gene ID: 127817183, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127817183
Gene description
H3K27ac hESC enhancer GRCh37_chr10:7407161-7407660
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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Location:
chromosome: 10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (7365199..7365698)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (7364917..7365416)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (7407161..7407660)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene Scm like with four mbt domains 2 Neighboring gene small nucleolar RNA, C/D box 129 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:7298769-7299968 Neighboring gene cytochrome c oxidase subunit 6C pseudogene 17 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2972 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:7371119-7371620 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2973 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2974 Neighboring gene uncharacterized LOC124902372 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr10:7403871-7405070 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:7449871-7450766 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2975 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2112 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:7453245-7454165 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:7454166-7455085 Neighboring gene uncharacterized LOC124902373 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:7487564-7487770 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:7488827-7489326 Neighboring gene long intergenic non-protein coding RNA 2642 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2977 Neighboring gene NANOG hESC enhancer GRCh37_chr10:7500249-7500813 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2978 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2979

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_118666.1 

    Range
    101..600
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    7365199..7365698
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    7364917..7365416
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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