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LOC127817728 OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42361019-42361799 [ Homo sapiens (human) ]

Gene ID: 127817728, updated on 12-Sep-2024

Summary

Gene symbol
LOC127817728
Gene description
OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42361019-42361799
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors and is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
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Genomic context

See LOC127817728 in Genome Data Viewer
Location:
chromosome: 10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (41878410..41879190)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (42152185..42152965)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (42361019..42361799, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:39078401-39079356 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:39079357-39080312 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:39080313-39081269 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:39081270-39082225 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:39082226-39083182 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:39083183-39084137 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:39084353-39084932 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:39084933-39085511 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:39087250-39087828 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:39087829-39088407 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:39093648-39094354 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:39094355-39095059 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:39107675-39108648 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:39111569-39112541 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:39108649-39109622 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:39109623-39110594 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:39110595-39111568 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:39106701-39107674 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:39105990-39106606 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:39105055-39105978 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:39119899-39120836 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:39121025-39121526 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:39140361-39141208 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:39137817-39138664 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:39138665-39139512 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:39139513-39140360 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:39136969-39137816 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:39136121-39136968 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:39144910-39145906 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:39148911-39149634 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:39149801-39150685 Neighboring gene ACTR3B pseudogene 5 Neighboring gene CHEK2 pseudogene 5 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42545591-42546107 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42545075-42545590 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42539347-42540296 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42535545-42536494 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42536495-42537444 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42537445-42538394 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42538395-42539346 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42540297-42541246 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42541247-42542196 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42542491-42543008 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42543009-42543524 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42543525-42544041 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42544042-42544557 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42544558-42545074 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42533643-42534592 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42526987-42527938 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42527939-42528888 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42528889-42529840 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42529841-42530790 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42530791-42531742 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42531743-42532692 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42532693-42533642 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42534593-42535544 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42409382-42409954 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42408808-42409381 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:42407978-42408555 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42407001-42407866 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42397944-42398710 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42398711-42399476 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42399477-42400242 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42400243-42401007 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42401509-42402010 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42403984-42404604 Neighboring gene NANOG hESC enhancer GRCh37_chr10:42405590-42406091 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42406133-42407000 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42402011-42402510 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42391746-42392698 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42387937-42388888 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42388889-42389840 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42389841-42390793 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42390794-42391745 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42392699-42393649 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42393650-42394602 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42394603-42395554 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42395555-42396506 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42396507-42397457 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42386985-42387936 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42377882-42378764 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42378765-42379646 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42379647-42380528 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42380529-42381409 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:42381502-42382100 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42382224-42383176 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42383177-42384128 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancers GRCh37_chr10:42385081-42386032 and GRCh37_chr10:42384129-42385080 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42386033-42386984 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42368179-42369060 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42369061-42369942 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42369943-42370824 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42370825-42371706 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42371707-42372588 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42373471-42374352 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42374353-42375235 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42375236-42376117 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42376118-42377000 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:42377001-42377881 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42372589-42373470 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42358679-42359458 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42357899-42358678 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42359459-42360238 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42360239-42361018 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42361800-42362579 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42363361-42364139 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42364140-42364920 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42364921-42365700 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42365701-42366480 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42366481-42367259 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42367296-42368178 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42362580-42363360 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42357119-42357898 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42356339-42357118 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:42355559-42356338 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42597433-42597968 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42600113-42600648 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42599577-42600112 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42599041-42599576 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42598505-42599040 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42597969-42598504 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:42596897-42597432 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:42661204-42662191 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:42663017-42663536 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:42663537-42664056 Neighboring gene NANOG hESC enhancer GRCh37_chr10:42664057-42664575 Neighboring gene formin-2-like Neighboring gene kinase suppressor of ras 1 pseudogene 1

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_119204.1 

    Range
    101..881
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    41878410..41879190
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    42152185..42152965
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)