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LOC127819811 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134208622-134209145 [ Homo sapiens (human) ]

Gene ID: 127819811, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127819811
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134208622-134209145
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127819811 in Genome Data Viewer
Location:
chromosome: 10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (132395118..132395641)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (133342683..133343206)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (134208622..134209145)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134001171-134001672 Neighboring gene dihydropyrimidinase like 4 Neighboring gene serine/threonine kinase 32C Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4222 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134056390-134057274 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134067757-134068258 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134068259-134068758 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134078043-134078543 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134096746-134097345 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:134111356-134111519 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2953 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134122180-134122724 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134122725-134123267 Neighboring gene Sharpr-MPRA regulatory region 5064 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4223 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:134144980-134145514 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2955 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4224 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:134152941-134153095 Neighboring gene leucine rich repeat containing 27 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134166187-134167149 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2956 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134203032-134203711 Neighboring gene uncharacterized LOC124902526 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134209146-134209668 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2958 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2959 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2960 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134211239-134211761 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134211762-134212284 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134214271-134215047 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134218733-134219360 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134221245-134221872 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134221873-134222500 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134222501-134223127 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134227291-134227958 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134231824-134232727 Neighboring gene PWWP domain containing 2B Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134232728-134233632 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2961 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2962 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2963 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134235443-134236346 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134237164-134237690 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:134244072-134244572 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134252266-134252930 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:134252931-134253594 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2964 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2965 Neighboring gene long intergenic non-protein coding RNA 3068

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_121280.1 

    Range
    101..624
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    132395118..132395641
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    133342683..133343206
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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