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LOC127820416 H3K27ac hESC enhancer GRCh37_chr11:10929292-10929928 [ Homo sapiens (human) ]

Gene ID: 127820416, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127820416
Gene description
H3K27ac hESC enhancer GRCh37_chr11:10929292-10929928
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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Location:
chromosome: 11
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (10907745..10908381)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (10992731..10993367)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:10879799-10880436 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:10880437-10881072 Neighboring gene ZBED5 antisense RNA 1 Neighboring gene uncharacterized LOC124902629 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:10920769-10921968 Neighboring gene uncharacterized LOC107984309 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr11:10929929-10930563 Neighboring gene Sharpr-MPRA regulatory region 6670 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3155 Neighboring gene uncharacterized LOC105379882 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3156 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:10958208-10958396 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:11058390-11058890 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:11058891-11059391 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:11086765-11087366 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:11089215-11089716 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:11089717-11090216 Neighboring gene OCT4 hESC enhancer GRCh37_chr11:11093610-11094115 Neighboring gene OCT4 hESC enhancer GRCh37_chr11:11117645-11118146 Neighboring gene long intergenic non-protein coding RNA 2752 Neighboring gene activating transcription factor 7 interacting protein 2 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_121875.1 

    Range
    101..737
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    10907745..10908381
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    10992731..10993367
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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